Author/Authors :
Feifei Gao، نويسنده , , Guangliang Zhang، نويسنده , , Suoqin Zhang، نويسنده , , Yueming Cheng، نويسنده , , Zhan Shi، نويسنده , , Yaoxian Li، نويسنده , , Junlong Gao، نويسنده ,
Abstract :
A three-component reaction of aromatic aldehydes, acetonitrile, and 2-thiohydantoins promoted by TiCl4 was discovered, and a different N–C–N bond-forming reaction took place with FeCl3, AlCl3 or BF3·Et2O as promoter. The thiohydantoin derivatives 1 and 3 were synthesized in moderate to high yields. A plausible mechanism for the formation of 1 and 3 is suggested.
