Title of article
A novel ambident reactivity of azolylacroleins
Author/Authors
Ildiko Nagy، نويسنده , , Gyorgy Hajos، نويسنده , , Zsuzsanna Riedl، نويسنده , , Orsolya Egyed، نويسنده , , Imre P?pai، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
7
From page
4730
To page
4736
Abstract
Reaction of azolylacroleins with phosphoranes bearing a conjugated double bond was found to yield either azolyltrienes in a Wittig reaction, or to undergo cyclization to a dihydrobenzene containing the azole substituent. Transformation with an aza-Wittig reagent gave tetrazolylpyridines. The ambident reactivity was found to be dependent on the substituent of the phosphorane, which was rationalized by ab initio (DFT) calculation of the atomic charges of the reaction centres.
Keywords
Wittig reaction , phosphorane , Azolyltriene , Ab initio calculation
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090832
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