Author/Authors :
Fulvio Gala، نويسنده , , Maria Valeria DʹAuria، نويسنده , , Simona De Marino، نويسنده , , Franco Zollo، نويسنده , , Charles D. Smith، نويسنده , , Jean E. Copper، نويسنده , , Angela Zampella، نويسنده ,
Abstract :
A reinvestigation of Jaspis splendans afforded the novel compounds jaspamide D–G plus the known compounds jaspamide and jaspamides B and C. All compounds exhibited potent cytotoxic activities and were shown to cause microfilament disruption. Biological activity and structural elucidation are reported here.