Title of article
Efficient synthesis of cephalotaxine- and deoxyharringtonine analogues by a trimethylaluminium-mediated domino reaction
Author/Authors
Lutz F. Tietze، نويسنده , , Holger Braun، نويسنده , , Peter L. Steck، نويسنده , , Serry A.A. El Bialy، نويسنده , , Nina T?lle، نويسنده , , Alexander Düfert، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
9
From page
6437
To page
6445
Abstract
The synthesis of cephalotaxine- and cephalotaxine amide analogues 14a–c and 16a–c as well as of the deoxyharringtonine analogues 5a,b was performed employing a trimethylaluminium-mediated domino reaction of 9a–c and 8 to give the spirocyclic compounds 7a–c, which was followed by a palladium catalyzed α-arylation.
Keywords
Palladium , domino reactions , Alkaloids , Spiro compounds , Harringtonines , cephalotaxine
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1091121
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