Pyridinium N-2′-pyridylaminide: radical cyclization for the synthesis of benzonaphthyridine derivatives

The synthesis of benzonaphthyridine derivatives that incorporate a 2-aminopyridine moiety can be performed by intramolecular radical pyridylation of the appropriate substrates, obtained from pyridinium N-2′-pyridylaminide, using TTMSS and AIBN.