• Title of article

    Synthesis of (2R,3R)-epigallocatechin-3-O-(4-hydroxybenzoate), a novel catechin from Cistus salvifolius, and evaluation of its proteasome inhibitory activities

  • Author/Authors

    Kumi Osanai، نويسنده , , Congde Huo، نويسنده , , Kristin R. Landis-Piwowar، نويسنده , , Q. Ping Dou، نويسنده , , Tak Hang Chan، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2007
  • Pages
    6
  • From page
    7565
  • To page
    7570
  • Abstract
    The total and semi syntheses of (2R,3R)-epigallocatechin-3-O-(4-hydroxybenzoate), a novel catechin from Cistus salvifolius, were accomplished. The proteasome inhibition and cytotoxic activities of the synthetic compound and its acetyl derivative were studied and compared with (2R,3R)-epigallocatechin-3-gallate (EGCG), the active component from green tea.
  • Journal title
    Tetrahedron
  • Serial Year
    2007
  • Journal title
    Tetrahedron
  • Record number

    1091346