Title of article
Investigation of macrocyclization sites for the synthesis of dendroamide A—an approach from a conformational search
Author/Authors
Takatoshi Matsumoto، نويسنده , , Eiichi Morishita، نويسنده , , Takayuki Shioiri، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
8571
To page
8575
Abstract
The systematic conformational analysis of three linear precursors for the synthesis of dendroamide A has revealed that these three precursors have the distance between the N- and C-terminal in the range of 3.43–3.93 Å, which suggests the possibility of macrocyclization. This result coincides with the results of the actual synthesis of dendroamide A, but contradicts the reported calculated results.
Keywords
Rational synthetic strategy , macrocyclization , Dendroamide A , Conformational analysis , cyclic peptide
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1091552
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