Author/Authors :
Chinatsu Ozawa، نويسنده , , Hironobu Hojo، نويسنده , , Yuko Nakahara، نويسنده , , Hidekazu Katayama، نويسنده , , Kazuki Nabeshima، نويسنده , , Toshiaki Akahane، نويسنده , , Yoshiaki Nakahara، نويسنده ,
Abstract :
Glycopeptide thioester comprising the sequence of extracellular matrix metalloproteinase inducer (emmprin) (34–58) was prepared and condensed with a dendrimer core having eight amino groups by the thioester method. The desired product, a glycopeptide dendrimer carrying an N-linked core pentasaccharide of about 30 kDa, was successfully isolated by preparative electrophoresis and characterized by mass analysis.