Author/Authors :
E.J. Amigues، نويسنده , , M.L. Greenberg، نويسنده , , S. Ju، نويسنده , , Y. Chen، نويسنده , , M.E. Migaud، نويسنده ,
Abstract :
The syntheses of cyclophosphodiesters of 5-C-(hydroxymethyl)-hexoses and hexitols and of 6-C-(hydroxymethyl)-hexoses are reported, along with that of 6-deoxy-gluco-heptose 7-phosphate. These compounds proved to be reasonable substrate mimics and show inhibitory activity against human d-myo-inositol 3-phosphate synthase.
