Cascade synthesis of benzofuran derivatives via laccase oxidation–Michael addition

The cascade synthesis of benzofuran derivatives was conducted from the reaction of catechols and 1,3-dicarbonyl compounds via oxidation–Michael addition in the presence of laccase and Sc(OTf)3/SDS. This reaction was carried out under air at room temperature in aqueous medium, and provided benzofuran products in moderate to good yields. In addition, this reaction system showed recyclability.