Author/Authors :
Philip C. Bulman Page، نويسنده , , Benjamin R. Buckley، نويسنده , , Mark R.J. Elsegood، نويسنده , , Colin M. Hayman، نويسنده , , Harry Heaney، نويسنده , , Gerasimos A. Rassias، نويسنده , , Salem A. Talib، نويسنده , , John Liddle، نويسنده ,
Abstract :
A number of enantiomerically pure 1,2-aminoalcohols containing tertiary nitrogen atoms bearing chiral substituents have been prepared by highly diastereoselective reductive ring cleavage of oxazolidines derived from ketones and pseudoephedrine or ephedrine. The ring cleavage occurs with retention of configuration.
Keywords :
Oxazolidine , Aminoalcohol , Reductive cleavage , Enantiomerically pure , Reduction , Stereoselective
