Author/Authors :
Shui-Chun Mao، نويسنده , , Emiliano Manzo، نويسنده , , Yue-Wei Guo، نويسنده , , Margherita Gavagnin، نويسنده , , Ernesto Mollo، نويسنده , , M. Letizia Ciavatta، نويسنده , , Rob van Soest، نويسنده , , Guido Cimino، نويسنده ,
Abstract :
Three unprecedented diastereoisomeric dimers, cis-dimer A (1), cis-dimer B (2) and trans-dimer C (3), exhibiting a bis-bisabolene skeleton, and a new sesquiterpene, dehydrotheonelline (4), their potential precursor, have been isolated from the South China Sea sponges Axinyssa variabilis and Lipastrotethya ana, along with known related sesquiterpenes. The structure of the novel molecules has been determined by extensive NMR spectral analysis.