Author/Authors :
Enrique Alvarez-Manzaneda، نويسنده , , Rachid Chahboun، نويسنده , , Faouzia Bentaleb، نويسنده , , Esteban Alvarez، نويسنده , , M. Angeles Escobar، نويسنده , , Said Sad-Diki، نويسنده , , Maria José Cano، نويسنده , , Ibtissam Messouri، نويسنده ,
Abstract :
Two procedures to introduce an oxygenated function into the C-14 of abietane diterpenes with complete regioselectivity have been developed. Utilizing these, the synthesis of the antileishmanial quinone (−)-12-deoxyroyleanone (1) and a formal synthesis of antitumour and immunosuppressant (−)-triptonide (7) and (−)-triptolide (8) from (+)-abietic acid (13) have been carried out.
Keywords :
Hydrazines , Enaminones , Cyclisation , Pyrazoles , Histamine analogues
