Title of article :
A simple and convenient one-pot method for the preparation of heteroaryl-2-imidazoles from nitriles
Author/Authors :
Matthew E. Voss، نويسنده , , Catherine M. Beer، نويسنده , , Scott A. Mitchell، نويسنده , , Peter A. Blomgren، نويسنده , , Paul E. Zhichkin، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
A simple, convenient and high-yielding one-pot method for the synthesis of 2-heterocycle-substituted imidazoles from the corresponding nitriles has been developed. The procedure is easily scaleable and the workup does not involve chromatography. This synthesis is also applicable to the preparation of imidazoles with electron-poor aryl substituents.
Keywords :
Cyclization , Imidazoles , Heterocycles , nitriles
Journal title :
Tetrahedron
Journal title :
Tetrahedron
