Author/Authors :
Dalia Fomekong Fotsop، نويسنده , , Fanny Roussi، نويسنده , , Catherine Le Callonec، نويسنده , , Hadjira Bousserouel، نويسنده , , Marc Litaudon، نويسنده , , Françoise Guéritte-Voegelein، نويسنده ,
Abstract :
Two new drimanes were isolated and characterized from the bark of Zygogynum baillonii, an endemic New-Caledonian tree of the Winteraceae family. One of it shows a significant cytotoxic activity. In order to define structure–activity relationships, analogues were synthesized and their cytotoxicity was evaluated.