Title of article
Three-component, one-pot diastereoselective synthesis of 4-amidotetrahydropyrans via the Prins–Ritter reaction sequence
Author/Authors
J.S. Yadav، نويسنده , , B.V. Subba Reddy، نويسنده , , S. Aravind، نويسنده , , G.G.K.S. Narayana Kumar، نويسنده , , C. Madhavi، نويسنده , , A.C Kunwar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
7
From page
3025
To page
3031
Abstract
Three-component coupling of carbonyl compounds, homoallylic alcohols, and nitriles has been achieved using 20 mol % of phosphomolybdic acid (PMA) at ambient temperature via the Prins–Ritter sequence to furnish 4-amidotetrahydropyrans in high yields with all cis selectivity. Spirocyclic-4-amidotetrahydropyrans are obtained using cyclic ketones.
Keywords
Prins–Ritter sequence , nitriles , Heteropolyacids , Amidotetrahydropyrans
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1093904
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