Author/Authors :
Mohamed M. Rammah، نويسنده , , Mohamed Othman، نويسنده , , Kabula Ciamala، نويسنده , , Carsten Strohmann، نويسنده , , Mohamed B. Rammah، نويسنده ,
Abstract :
γ-Acetylenic carboxylic acids are cyclized to spirolactones under mild conditions, in the presence of Ag2CO3 catalyst. The corresponding spiro-5-alkylidene-γ-butyrolactones were isolated in high yields, and this process constitutes an easy and efficient route to analogous structures of natural products of biological interest.
