Formation of chiral 21-helical columnar host system with phenylacetylene unit by using (1R,2S)-2-amino-1,2-diphenylethanol

A tunable supramolecular phenylacetylene host system with a chiral channel-like cavity is developed by using (1R,2S)-2-amino-1,2-diphenylethanol. This host system possesses a chiral 21-helical columnar structure; chiral cavities are constructed by the self-assembly of the 21-helical column, and guest molecules are included by varying the packing of this column.