Title of article :
A simple and convenient synthesis of 4-methyl-3-nitro-2-trihalomethyl-2H-chromenes from N-unsubstituted imines of 2-hydroxyacetophenones and trichloro(trifluoro)ethylidene nitromethanes
Author/Authors :
Vladislav Yu. Korotaev، نويسنده , , Vyacheslav Ya Sosnovskikh، نويسنده , , Igor B. Kutyashev، نويسنده , , Alexey Yu. Barkov، نويسنده , , Evgeniya G. Matochkina، نويسنده , , Mikhail I. Kodess، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
The reaction of N-unsubstituted imines of 2-hydroxyacetophenones with trichloro(trifluoro)ethylidene nitromethanes in the presence of DABCO proceeds via tandem oxa-Michael/aza-Henry additions (in dichloromethane) or aza-Michael addition (in benzene) to give 4-methyl-3-nitro-2-trichloro(trifluoro)methyl-2H-chromenes or 1,1,1-trichloro(trifluoro)-3-nitro-N-[1-(2-hydroxyaryl)ethylidene]propan-2-amines, respectively.
Keywords :
2-Hydroxyacetophenones imines , Nitroalkenes , Michael addition , 4-Methyl-2H-chromenes , Trihalomethylated compounds
Journal title :
Tetrahedron
Journal title :
Tetrahedron
