Title of article
Aplicyanins A–F, new cytotoxic bromoindole derivatives from the marine tunicate Aplidium cyaneum
Author/Authors
Fernando Reyes ، نويسنده , , Rogelio Fernandez، نويسنده , , Alberto Rodriguez-Ardila and Charles Bonatto، نويسنده , , Andrés Francesch، نويسنده , , Sergi Taboada، نويسنده , , Conxita Avila، نويسنده , , Carmen Cuevas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
5119
To page
5123
Abstract
Six new bromoindole derivatives, aplicyanins A–F (1–6), have been isolated from the CH2Cl2/MeOH extract of the tunicate Aplidium cyaneum collected in Antarctica. Their structures were determined by extensive analysis of their spectroscopic features, particularly 1D and 2D NMR spectra, and comparison with related compounds. Cytotoxic and antimitotic activities were found for compounds 2 and 4–6.
Keywords
Antarctic tunicates , Bromoindole , Antimitotic , marine metabolites , Cytotoxicity
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094116
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