A prominent C-acylation–cyclisation synthetic sequence and X-ray structure elucidation of benzothiopyranone derivatives

A novel short-step methodology to benzothiopyranone derivatives has been developed starting from an activated precursor, N-hydroxysuccinimide ester of thiosalicylic acid. The procedure is based on a tandem C-acylation–cyclisation process under mild reaction conditions in good yields. The structure elucidation has been established using X-ray crystallography and NMR spectral data.