Author/Authors :
Francisco A. Macias، نويسنده , , David Chinchilla، نويسنده , , José M.G Molinillo، نويسنده , , Frank R. Fronczek، نويسنده , , Kozo Shishido، نويسنده ,
Abstract :
Both epimers of Heliannuol A, first heliannane reported in the literature, isolated from Heliannthus annuus, have been prepared individually in a stereoselective route using a ring closing metathesis (RCM) as a key step to obtain the eight-membered ring. Very good overall yield was obtained in both cases.