Title of article
First asymmetric Abramov-type phosphonylation of aldehydes with trialkyl phosphites catalyzed by chiral Lewis bases
Author/Authors
Kyoko Nakanishi، نويسنده , , Shunsuke Kotani، نويسنده , , Masaharu Sugiura، نويسنده , , Makoto Nakajima، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
6415
To page
6419
Abstract
Chiral phosphine oxides (Lewis bases) catalyze silicon tetrachloride-mediated, enantioselective phosphonylation of aldehydes with trialkyl phosphites (Abramov-type reaction), which leads to optically active α-hydroxyphosphonates with moderate enantioselectivities. 31P NMR analysis of the phosphonylation of benzaldehyde with triethyl phosphite supports the assumed reaction mechanism.
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094274
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