Author/Authors :
Dimitri M. Khramov، نويسنده , , Evelyn L. Rosen، نويسنده , , Joyce A.V. Er، نويسنده , , Peter D. Vu، نويسنده , , Vincent M. Lynch، نويسنده , , Christopher W. Bielawski، نويسنده ,
Abstract :
The effect of tuning the electronic properties of N-heterocyclic carbene (NHC) ligands was evaluated in multiple, mechanistically distinct, metal-mediated reactions. Hydroboration and Heck reactions, catalyzed by Rh–NHC and Pd–NHC complexes, respectively, were found to result in yields that were up to ten times lower when π-withdrawing substituents were incorporated into the NHC backbone relative to analogues bearing σ-withdrawing groups.
