Author/Authors :
Lensey L. Hill، نويسنده , , Joanna M. Smith، نويسنده , , William S. Brown، نويسنده , , Lucas R. Moore، نويسنده , , Paul Guevera، نويسنده , , Emily S. Pair، نويسنده , , Jake Porter، نويسنده , , Joe Chou، نويسنده , , Christopher J. Wolterman، نويسنده , , Raluca Craciun، نويسنده , , David A. Dixon، نويسنده , , Kevin H. Shaughnessy، نويسنده ,
Abstract :
The use of neopentylphosphine ligands in the palladium-catalyzed Suzuki, Sonogashira, Heck, and Hartwig–Buchwald couplings of aryl bromides and chlorides are reported. Di-tert-butylneopentylphosphine (DTBNpP) provided highly active catalysts for the coupling of aryl bromides at mild temperatures. Trineopentylphosphine, an air-stable trialkylphosphine, gave inactive catalysts at room temperature, but showed good activity in the H–B amination of aryl chlorides at elevated temperatures.
