Title of article :
Synthesis of a spiroacetal moiety of antitumor antibiotic ossamycin by anodic oxidation
Author/Authors :
Eriko Honjo، نويسنده , , Noriki Kutsumura، نويسنده , , Yuichi Ishikawa، نويسنده , , Shigeru Nishiyama، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Synthesis of the spiroacetal moiety (C20–C33) of the antitumor antibiotic ossamycin, is reported. Anodic oxidation of the dithioacetal effected simultaneous removal of the protecting group and acetalization to afford the corresponding 6,6-spiroacetal structure in excellent yield.
Keywords :
Antibiotics , Ossamycin , Anodic oxidation , Spiroacetal
Journal title :
Tetrahedron
Journal title :
Tetrahedron