Title of article
A class of 18(13→14)-abeo-schiartane skeleton nortriterpenoids from Schisandra propinqua var. Propinqua
Author/Authors
Chun Lei، نويسنده , , Jian-Xin Pu، نويسنده , , Sheng-Xiong Huang، نويسنده , , Ji-Jun Chen، نويسنده , , Jingping Liu، نويسنده , , Li-Bin Yang، نويسنده , , Yun-bao Ma، نويسنده , , Wei-Lie Xiao، نويسنده , , Xiaonian Li، نويسنده , , Han-Dong Sun، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
7
From page
164
To page
170
Abstract
A class of C29 triterpene dilactones (1–6) featuring 18(13→14)-abeo-schiartane skeleton have been isolated from the stems of Schisandra propinqua var. propinqua. The structures of new compounds, propindilactones K–O (1–5), were determined on the basis of comprehensive spectroscopic means. Biogenetic pathway of 1–6 was proposed and then chemically mimicked. The absolute stereochemistries of new compounds were established on biosynthetic consideration coupled with CD experiments. Compound 2 showed promising anti-HBV activity in vitro.
Keywords
2-Migration , Chemical mimic , Anti-HBV activity , Schisandra , 1 , Lactone , Nortriterpenoid
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1094951
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