Acremines H–N, novel prenylated polyketide metabolites produced by a strain of Acremonium byssoides

Five novel metabolites, acremines H–N, have been isolated from malt extract–peptone–glucose agar cultures of a strain of Acremonium byssoides. Their structures and stereochemistry were elucidated using a combination of 13C and 1H homo and heteronuclear 2D NMR experiments. Acremines H–N inhibited the germination of sporangia of Plasmopara viticola.