Author/Authors :
Issa Samb، نويسنده , , Nadia Pellegrini-Moïse، نويسنده , , Sandrine Lamandé-Langle، نويسنده , , Yves Chapleur، نويسنده ,
Abstract :
Efficient reaction conditions have been developed to prepare highly functionalized chiral pyranosido-pyrimidine by regioselective alkylation of the pyranoside ring and palladium-catalyzed cross-coupling reaction on the pyrimidine ring under microwave activation. Such scaffold contains three different functions suitable for selective derivatization and could find applications in the design of peptidomimetics.
