Author/Authors :
Helge Menz، نويسنده , , J?rg T. Binder، نويسنده , , Benedikt Crone، نويسنده , , Alexander Duschek، نويسنده , , Timm T. Haug، نويسنده , , Stefan F. Kirsch، نويسنده , , Philipp Klahn، نويسنده , , Clémence Liébert، نويسنده ,
Abstract :
Gold-catalyzed reactions of 3-silyloxy-1,5-enynes in the presence of sterically demanding alcohols afford 4-acylcyclopentenes. The cascade process most likely proceeds through a 6-endo-dig carbocyclization and subsequent pinacol-type rearrangement. Studies that define scope and limitations of the cyclization–migration strategy are also described. An alternative cascade yields highly substituted aryls through an unprecedented cyclization–fragmentation pathway.
