Author/Authors :
Artur J?gi، نويسنده , , Anne Paju، نويسنده , , T?nis Pehk، نويسنده , , Tiiu Kailas، نويسنده , , Aleksander-Mati Müürisepp، نويسنده , , Margus Lopp، نويسنده ,
Abstract :
A series of 4′-aryl-2′,3′-dideoxynucleoside analogues were synthesized from optically pure 5-oxo-2-aryl-tetrahydrofuran-2-carboxylic acids up to 62% overall yield. 5-Oxo-2-aryl-tetrahydrofuran-2-carboxylic acids were obtained from 2-hydroxy-3-arylcyclopent-2-en-1-ones by asymmetric oxidation in up to 38–57% yield.
