Title of article
Selective mono- and di-N-alkylation of aromatic amines with alcohols and acylation of aromatic amines using Ph3P/DDQ
Author/Authors
Nasser Iranpoor، نويسنده , , Habib Firouzabadi، نويسنده , , Najmeh Nowrouzi، نويسنده , , Dariush Khalili، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
7
From page
3893
To page
3899
Abstract
Selective N-monoalkylation of aromatic amines with 1° and 2° alcohols and conversion of aromatic amines to amides are performed immediately and in excellent yields using triphenylphosphine (PPh3) and 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) in dichloromethane at room temperature. Symmetrical and unsymmetrical N,N-dialkylation of aromatic amines are also carried out in modest yield at room temperature by this reagent system.
Keywords
N , Amide , Aromatic amine , N-Dialkylation , Triphenylphosphine , DDQ , Carboxylic acid , N-Monoalkylation
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1095404
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