Title of article
Gelegamines A–E: five new oxindole alkaloids from Gelsemium elegans
Author/Authors
Zhen Zhang، نويسنده , , Ying-Tong Di، نويسنده , , Yue-Hu Wang، نويسنده , , Zhen Zhang، نويسنده , , Shu-Zhen Mu، نويسنده , , Xin-Fang Wang، نويسنده , , Yu Zhang، نويسنده , , Cheng-jian Tan، نويسنده , , Qiang Zhang، نويسنده , , Xiao-Hui Yan، نويسنده , , Jie Guo، نويسنده , , Chun-Shun Li، نويسنده , , Xiao-Jiang Hao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
6
From page
4551
To page
4556
Abstract
Five new oxindole alkaloids, gelegamines A–E (1–5), were isolated from the roots of Gelsemium elegans. Their structures were extensively elucidated on the basis of spectroscopic analysis. Among them, the epoxy ring (C-19/C-20) of gelegamine A (1) was assigned as α-orientation by ROESY experiment and DFT method at B3LYP/6-31g(d) level, and gelegamine B (2) is the first humantenine-type alkaloid with 19-(E) ethylidene configuration. The absolute configurations of gelegamines A–E (1–5) were established on biosynthetic consideration coupled with CD experiments.
Keywords
Loganiaceae , Gelsemium elegans , oxindole alkaloid , Gelegamines A–E
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1095479
Link To Document