Title of article :
Chiral Brønsted acid-catalyzed hydrophosphonylation of imines—DFT study on the effect of substituents of phosphoric acid
Author/Authors :
Takahiko Akiyama، نويسنده , , Hisashi Morita، نويسنده , , Prabhakar Bachu، نويسنده , , Keiji Mori، نويسنده , , Masahiro Yamanaka، نويسنده , , Takashi Hirata، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
The enantioselective hydrophosphonylation reaction of diisopropyl phosphite with aldimine furnished α-amino phosphonates with high enantioselectivities by means of a chiral phosphoric acid. DFT calculation of the effect of 3,3′-substituents of the phosphoric acid revealed the reason for the high enantioselectivities.
Keywords :
Phosphoric acid , Hydrophosphonylation , Chiral Br?nsted acid , ?-Amino phosphonate , DFT calculation
Journal title :
Tetrahedron
Journal title :
Tetrahedron
