Title of article
Synthesis of 5-arylthiazoles. Comparative study between Suzuki cross-coupling reaction and direct arylation
Author/Authors
Nicolas Primas، نويسنده , , Alexandre Bouillon، نويسنده , , Jean-Charles Lancelot، نويسنده , , Hussein El-Kashef، نويسنده , , Sylvain Rault، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
8
From page
5739
To page
5746
Abstract
A facile synthetic route to the new thiazol-5-ylboronic acid pinacol ester was described herein. Its reactivity toward Suzuki cross-coupling reaction was studied to provide various 5-arylthiazoles. A comparative study between Suzuki cross-coupling reactions and palladium-catalyzed C5–H direct arylation on thiazole ring was achieved.
Keywords
boronic ester , Suzuki cross-coupling , Direct arylation , aryl halides , Thiazole
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1097277
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