Title of article :
Study on the cyclization of 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine: microwave versus thermal preparation of pyrido[4,3-d]pyrimidines
Author/Authors :
Inga Cikotiene، نويسنده , , Visvaldas Kairys، نويسنده , , Rita Buksnaitiene، نويسنده , , Marius Morkunas، نويسنده , , Simonas Rudys، نويسنده , , Algirdas Brukstus، نويسنده , , Miguel X. Fernandes، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
Thermal and microwave initiated cyclization of 2,4-disubstituted 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine has been studied. A novel high-yielding preparation of 2,4-disubstituted 7-arylpyrido[4,3-d]pyrimidines has been developed. The intermediate compounds were isolated and possible mechanism of the reactions is discussed.
Keywords :
1 , 6-Electrocyclic reaction , Cyclization , 6-Arylethynylpyrimidine-5-carbaldehydes , 3-d]pyrimidines , Microwave
Journal title :
Tetrahedron
Journal title :
Tetrahedron
