Title of article
Synthesis of 2-TIPS-oxazol-5-ylboronic acid pinacol ester: efficient route to 5-(het)aryloxazoles via Suzuki cross-coupling reaction
Author/Authors
Nicolas Primas، نويسنده , , Alexandre Bouillon، نويسنده , , Jean-Charles Lancelot، نويسنده , , Sylvain Rault، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
6
From page
6348
To page
6353
Abstract
A facile synthetic route to the new 2-TIPS-oxazol-5-ylboronic acid pinacol ester was described herein. Its reactivity toward Suzuki cross-coupling reaction was studied to provide various 5-(het)aryloxazoles. A wide range of functions on the aryl moiety are tolerated.
Keywords
Suzuki cross-coupling , aryl halides , boronic ester , oxazole , Silyl protecting group
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1097476
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