Title of article :
Synthesis and preliminary evaluation of duocarmycin analogues incorporating the 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[2,3-e]indol-4-one (CNI) and 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[1,2-e]indol-4-one (iso-CNI) alkylation subunits
Author/Authors :
Carla M. Gauss، نويسنده , , Akiyuki Hamasaki، نويسنده , , Jay P. Parrish، نويسنده , , Karen S. MacMillan، نويسنده , , Thomas J. Rayl، نويسنده , , Inkyu Hwang، نويسنده , , Dale L. Boger، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
Efficient syntheses and a preliminary evaluation of 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[2,3-e]-indole (CNI) and 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[1,2-e]indole (iso-CNI), and their derivatives containing an anthracene and phenanthrene variant of the CC-1065 or duocarmycin alkylation subunit are detailed.
Journal title :
Tetrahedron
Journal title :
Tetrahedron
