Author/Authors :
Bj?rn C.G. S?derberg، نويسنده , , Sobha P. Gorugantula، نويسنده , , Chet R. Howerton، نويسنده , , Jeffrey L. Petersen، نويسنده , , Shubhada W. Dantale، نويسنده ,
Abstract :
An inherently regiospecific synthesis of isatins (1H-indole-2,3-diones) starting from 1-halo-2-nitrobenzenes is described. The isatins are formed by an intramolecular palladium-catalyzed annulation of 2-(2-haloethynyl)-1-nitrobenzenes via the formation of 2-haloisatogens.
