Towards the total synthesis of Calyculin C: preparation of the C13–C25 spirocyclic core
Author/Authors :
Damien Habrant، نويسنده , , Alan J.W. Stewart، نويسنده , , Ari M.P. Koskinen، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Pages :
8
From page :
7927
To page :
7934
Abstract :
A stereoselective synthesis of the C13–C25 of Calyculin C is described. Key steps involve the coupling of a terminal acetylene with a thiol ester and subsequent spirocyclisation using a double intramolecular hetero-Michael addition.
