Title of article
Highly enantioselective desymmetrization of meso- and prochiral cyclic ketones via organocatalytic Michael reaction
Author/Authors
Jia-Rong Chen، نويسنده , , Yuan-Yuan Lai، نويسنده , , Haihua Lu، نويسنده , , Xu-Fan Wang، نويسنده , , Wen-Jing Xiao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
6
From page
9238
To page
9243
Abstract
An efficient and novel organocatalyst has been developed for the asymmetric desymmetrization of meso- and prochiral ketones by direct Michael addition to nitroolefins. This strategy can afford the desymmetrization products with excellent diastereo- (up to >99:1) and enantioselectivity (up to 96%) in great yields (up to 95%).
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1099196
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