Title of article
Pyrrolidine–pyridine base catalysts for the enantioselective Michael addition of ketones to chalcones
Author/Authors
Da-Zhen Xu، نويسنده , , Bao-Sen Shi، نويسنده , , Yingjun Liu، نويسنده , , Yongmei Wang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
6
From page
9344
To page
9349
Abstract
A series of pyrrolidine–pyridine base organocatalysts have been developed and 3a found to be a highly effective catalyst for the asymmetric Michael addition reactions of ketones to chalcones. The reaction generated the corresponding products 1, 5-diketones in excellent diastereoselectivities (up to >99:1 dr) and enantioselectivities (up to 100% ee).
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1099210
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