Author/Authors :
Asako Toyoda، نويسنده , , Hazuki Nagai، نويسنده , , Tomonari Yamada، نويسنده , , Yusuke Moriguchi، نويسنده , , Junko Abe، نويسنده , , Toshio Tsuchida، نويسنده , , Kazuo Nagasawa، نويسنده ,
Abstract :
19-Norvitamin D analogs 3a and 3b were synthesized from 25-hydroxyvitamin D, obtained via a bioconversion method. The synthetic route features a highly regio- and stereoselective hydroboration reaction to afford 25-hydroxy-3,5-cyclopropyl-vitamin D derivatives 12 having olefin at the C1–10-position.
