Author/Authors :
Carmen Festa، نويسنده , , Simona De Marino، نويسنده , , Valentina Sepe، نويسنده , , Maria Chiara Monti، نويسنده , , Paolo Luciano، نويسنده , , Maria Valeria DʹAuria، نويسنده , , Cécile Debitus، نويسنده , , Mariarosaria Bucci، نويسنده , , Valentina Vellecco، نويسنده , , Angela Zampella، نويسنده ,
Abstract :
Two new metabolites, perthamides C and D, have been isolated from the marine sponge Theonella swinhoei. Their structures were determined by interpretation of NMR and ESIMS data. All compounds exhibited in vivo potent anti-inflammatory activity. Biological activity and structural elucidation are reported.