Title of article :
SmI2-mediated dialdehyde ‘radical then aldol’ cyclization cascades: a feasibility study
Author/Authors :
Matthew D. Helm، نويسنده , , Madeleine Da Silva، نويسنده , , David Sucunza، نويسنده , , Madeleine Helliwell، نويسنده , , David J. Procter، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
Dialdehydes undergo ‘radical then aldol’ cyclization cascades upon treatment with SmI2, generating four contiguous stereocenters with high diastereocontrol. The scope of the process has been explored and the cascade has been extended to also include lactone reduction.
Keywords :
Samarium , Cyclization , Cascade , Radical
Journal title :
Tetrahedron
Journal title :
Tetrahedron
