Author/Authors :
Firouz Matloubi Moghaddam، نويسنده , , Zohreh Mirjafary، نويسنده , , Hamdollah Saeidian، نويسنده , , Salman Taheri، نويسنده , , Malihe Doulabi، نويسنده , , Mostafa Kiamehr، نويسنده ,
Abstract :
An efficient, single step synthesis of hitherto unknown indole-annulated pentacyclic indolylhydroquinolines via tandem C-alkylation and intramolecular S-alkylation of indolin-2-thiones with N-alkylquinolinium salts in excellent yields (83–95%) is reported. This facile approach provides a powerful entry into polycyclic structures containing nitrogen and sulfur related to alkaloids. The structure of the product was determined by Röntgen crystal structure analysis.
