Author/Authors :
Marina Gruit، نويسنده , , Dirk Michalik، نويسنده , , Karolin Krüger، نويسنده , , Anke Spannenberg، نويسنده , , Annegret Tillack، نويسنده , , Anahit Pews-Davtyan، نويسنده , , Matthias Beller، نويسنده ,
Abstract :
The synthesis of potentially bioactive pyrroloazepinones based on the catalytic intramolecular cyclization of alkyne-substituted 1H-pyrrole-2-carboxylic acid amides has been developed. In the presence of either H2PtCl6·6H2O at 120 °C or AuCl3 at room temperature pyrrolo[3,2-c]azepin-4-ones are formed.
Keywords :
pyrroles , alkynes , Platinum , Cyclization , Gold
