Title of article
Titanocene (III) chloride mediated radical induced synthesis of (−)-methylenolactocin and (−)-protolichesterinic acid
Author/Authors
Sumit Saha، نويسنده , , Subhas C. Roy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
6
From page
4278
To page
4283
Abstract
Enantioselective synthesis of two anti-tumor antibiotics, (−)-methylenolactocin and (−)-protolichesterinic acid, has been achieved through titanocene(III) chloride mediated radical cyclization reaction starting from commercially available d-mannitol. Titanocene(III) chloride (Cp2TiCl) was prepared in situ from commercially available titanocene dichloride (Cp2TiCl2) and zinc dust in THF.
Keywords
Titanocene(III) chloride , Radical , Methylenolactocin , Protolichesterinic acid , Enantioselective
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1100904
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