Title of article
Enantioselective syntheses of both enantiomers of cis-pyrrolidine 225H
Author/Authors
Hong Shu، نويسنده , , April R. Noble، نويسنده , , Suhong Zhang، نويسنده , , Lei Miao، نويسنده , , Mark L. Trudell، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
6
From page
4428
To page
4433
Abstract
The efficient and expeditious syntheses of both enantiomers of the amphibian alkaloid cis-225H have been achieved. Utilizing a common cis-2,5-disubstituted pyrrolidine building block derived from (+)-2-tropinone, the enantioselective syntheses have established the absolute configuration of these alkaloids as (+)-(2R,5S) and (−)-(5S,2R).
Keywords
Ant venom alkaloids , Amphibian alkaloids , Enantioselective synthesis , Pyrrolidine
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1100921
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