Title of article
Preparation and biological evaluation of key fragments and open analogs of scleritodermin A
Author/Authors
Diver Sellanes، نويسنده , , Francisco Campot، نويسنده , , Ivana N??ez، نويسنده , , Gerardo Lin، نويسنده , , Pablo Esp?sito، نويسنده , , Sylvia Dematteis، نويسنده , , Jenny Salda?a، نويسنده , , Laura Dom?nguez، نويسنده , , Eduardo Manta، نويسنده , , Gloria Serra، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
12
From page
5384
To page
5395
Abstract
The synthesis of key fragments of scleritodermin A, their assembly, and their biological evaluation as cytotoxic and anthelmintic were performed. Highlights of the synthetic route include formation of the α-ketoamide linkage and use of stereocontrolled reactions. Open analogs of this natural product were obtained using a convergent strategy.
Keywords
Scleritodermin A analogs , azoles , ?-ketoamide , Key fragments
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1101040
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